Metabolism: Buprenorphine undergoes metabolism by cytochrome CYP3A4 enzymes soon after it enters your body and forms an Energetic metabolite, norbuprenorphine, with weak intrinsic action.Subutex is a brand name name for your drug that contains buprenorphine, a partial opioid agonist used for the cure of opioid dependence.1 Although the Subutex tra